Department of Molecular Physiology
and Biological Physics
at the University of Virginia
The lab is located at the Department of Molecular Physiology and Biological Physics. We are a member group at the Center for Membrane and Cell Physiology.
Our group is interested in understanding how newly-made proteins localize to sub-cellular compartments in health and disease.
To this end, our aim is to determine the structural and functional basis of the protein targeting machinery in the cargo recognition and delivery mode to the membranes of these compartments.
We use a combination of integrative research approaches including molecular and structural biology, biochemical, and biophysical techniques with main focus on single particle cryo-electron microscopy.